The line-up for Clear Channel’s iHeartRadio Music Festival 2012 was unveiled this morning via special live announcement by Ryan Seacrest—and it looks to be another once in a lifetime event.

Rihanna, Taylor Swift, Aerosmith, Usher, Bon Jovi, Lil Wayne, Green Day, Miranda Lambert, Mary J. Blige, Shakira and others are set to take the stage at the iHeartRadio Music Festival 2012 this fall in Las Vegas.

The stellar lineup suggests the two-day marketing blitz to promote Clear Channel’s iHeartRadio digital music service is on its way to repeating the success of last year’s debut concert.

Clear Channel, which also owns 850 terrestrial radio stations in the U.S., says Brad Paisley, Pitbull, Enrique Iglesias, No Doubt, Linkin Park, Jason Aldean, P!nk, deadmau5, Swedish House Mafia and Calvin Harris are also among the performers set for the festival on Sept. 21 and 22 at the MGM Grand. Ryan Seacrest will introduce the first night’s show.

The two-day festival will be streamed live by Yahoo!, Clear Channel’s web and mobile webcast partner for the event.

This year’s iHeartRadio Music Festival follows last year’s inaugural event–tickets for which sold out 10 minutes after being made available to the public—and likewise has focused on superstar talent.

“Last year’s iHeartRadio Music Festival had so many acts from so many different genres on one stage, a true rarity for a concert,” Seacrest told The Associated Press Monday. “This year it’s set to be bigger and better, with an unbelievable roster of some of the most talented names in the music business.”

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